Search results for " Design of experiments"

showing 10 items of 11 documents

A statistical design of experiments for optimizing the MALDI-TOF-MS sample preparation of polymers. An application in the assessment of the thermo-me…

2011

[EN] The sample preparation procedure for MALDI-TOF MS of polymers is addressed in this study by the application of a statistical Design of Experiments (DoE). Industrial poly (ethylene terephthalate) (PET) was chosen as model polymer. Different experimental settings (levels) for matrixes, analyte/matrix proportions and concentrations of cationization agent were considered. The quality parameters used for the analysis were signal-to-noise ratio and resolution. A closer inspection of the statistical results provided the study not only with the best combination of factors for the MALDI sample preparation, but also with a better understanding of the influence of the different factors, individua…

Solucions polimèriquesEthylenePolymersAnalytical chemistryDegradation kineticsBiochemistryThermo-mechanical degradationSample preparation procedureAnalytical ChemistryMatrix (chemical analysis)chemistry.chemical_compoundDegradationGlycolsMatrix assisted laser desorption ionization time of flight mass spectrometryPolyethylene terephthalateMechanismsCationizationSample preparationRecyclingMechanical recyclingSpectroscopyPriority journalchemistry.chemical_classificationDithranolSignal to noise ratioPolyethylene terephthalateHydrolysisMultiple processingPolymerPoly (ethylene terephthalate)Potential reactionsInjection cyclesMAQUINAS Y MOTORES TERMICOSInductively coupled plasmaSimulationEthersMatrix-assisted laser desorption/ionization time-of-flightQuality parametersDesign of ExperimentsGlycol unitsSample preparationArticleEthyleneEnvironmental ChemistryPolyethylene terephthalatesMALDI TOF MSSignal noise ratioMass spectrometryMatrixTermoplàsticsSignal to noiseTransesterificationDegradation mechanismMatrix-assisted laser desorption/ionizationStatistical design of experimentsTransesterificationchemistryChemical engineeringOligomersDesorptionEthylene glycolControlled studyProcess optimizationAnalytica chimica acta
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Managerial Behavior in the Lab: Information Disclosure, Decision Process and Leadership Style

2019

This paper reports the results from a lab experiment in which subjects playing the manager role can implement either an efficient / inegalitarian allocation or an inefficient / egalitarian allocation of payoffs. The experiment simulates a stylized managerial context by allowing the manager to manipulate information and select the decision process and by allowing the stakeholders to retaliate against the manager given different choices in the decision process. We found that the inefficient allocation is often selected and that this choice depends on whether the employees can retaliate against the manager and on whether the manager can hide information about the payoffs. The social preference…

JEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C92 - Laboratory Group BehaviorStylized factDecision process050208 financeManagerial decisionAsymmetric informationProcess (engineering)Management style.05 social sciencesStochastic gameManagement stylesCommunication strategyContext (language use)JEL: M - Business Administration and Business Economics • Marketing • Accounting • Personnel Economics/M.M1 - Business Administration/M.M1.M12 - Personnel Management • Executives; Executive Compensation[SHS.ECO]Humanities and Social Sciences/Economics and FinanceSocial preferencesMicroeconomicsInformation asymmetry0502 economics and businessJEL: D - Microeconomics/D.D3 - Distribution/D.D3.D39 - OtherLeadership styleBusiness050207 economics[SHS.ECO] Humanities and Social Sciences/Economics and Finance
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"Facta non verba" : an experiment on pledging and giving

2015

International audience; We design an experiment to investigate whether asking people to state how much they will donate to a charity (i.e., to pledge) increases their actual donation. Individuals’ endowment is either certain or a random variable. We study different types of pledges, namely, private, public and irrevocable, which differ in terms of the cost to the individual for not keeping the promise. We show that in absence of endowment uncertainty, private and public pledges are associated with lower donations as compared to donations in the no-pledge case: private pledges slightly reduce donations and public pledges reduce them more significantly. Donations increase with uncertainty (in…

Economics and EconometricsSociology and Political Sciencecharitable givingEndowmentmedia_common.quotation_subject050109 social psychologyMonetary economicsjel:D64Pledgejel:D03Dictator gameState (polity)Political sciencedictator game0502 economics and businessEconomics0501 psychology and cognitive sciencesStatistical dispersionJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C91 - Laboratory Individual BehaviorJEL: D - Microeconomics/D.D6 - Welfare Economics/D.D6.D64 - Altruism • Philanthropy050207 economicsApplied PsychologyPledgemedia_commonLaw and economicsjel:C91business.industryCommunication05 social sciencesCharity givingPublic relations[SHS.ECO]Humanities and Social Sciences/Economics and FinanceCharity givingPledgeCommitmentCommunicationExperimentsCommitmentDonation[SHS.GESTION]Humanities and Social Sciences/Business administrationbusinessExperimentsJEL: D - Microeconomics/D.D0 - General/D.D0.D03 - Behavioral Microeconomics: Underlying PrinciplesCharity giving; Pledge; Commitment; Communication; ExperimentsJEL: D - Microeconomics/D.D0 - General
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El esfuerzo en el trabajo de los docentes: el impacto del experimento AGEMAD

2014

International audience; Utilizando datos de un experimento randomizado realizado en Madagascar durante dos años escolares completos, se evalúan las heterogeneidades de impacto de unas intervenciones específicamente diseñadas para mejorar la gestión del proceso pedagógico en la escuelas primarias. Nuestros resultados muestran que intervenciones intensivas y directas a lo largo de la jerarquía educativa permiten cambiar el comportamiento de los docentes de manera significativa. Sin embargo, el impacto medio del programa oculta una gran heterogeneidad. Los maestros que tenían pocos alumnos así como los que tenían unas buenas condiciones de trabajo se beneficiaron más de las mismas. Por el cont…

JEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policy[SHS.EDU]Humanities and Social Sciences/EducationJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field Experiments[SHS.EDU] Humanities and Social Sciences/Educationdocentesexperimento randomizado[ SHS.EDU ] Humanities and Social Sciences/EducationJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of Education[SHS.ECO]Humanities and Social Sciences/Economics and Financeeducación primariaJEL : C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field ExperimentsMadagascar[ SHS.ECO ] Humanities and Social Sciences/Economies and finances[SHS.ECO] Humanities and Social Sciences/Economics and FinanceJEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of EducationJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policy
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Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly…

2011

[EN] Multiple processing by means of successive injection cycles was used to simulate the thermo-mechanical degradation effects on the oligomeric distribution of PLA under mechanical recycling. Likewise, an accelerated thermal ageing over PLA glass transition was performed in order to simulate its service life. MALDI-TOF MS was used for the analysis and the sample preparation procedure was assessed by means of a statistical Design of Experiments (DoE). The quality effects in use for the analysis were signal-to-noise ratio and Resolution. Different matrixes, analyte/matrix proportions and the use of NaTFA as cationization agent were considered. A deep inspection of the statistical results pr…

Solucions polimèriquesPolymers and PlasticsGeneral Physics and AstronomyTransesterificationsThermo-mechanical degradationSample preparation procedureMatrix (chemical analysis)DegradationMechanismsMaterials ChemistryCationizationMechanical recyclingSample preparationRepeating unitPoly(lactide)Signal to noise ratioChemistryMultiple processingDesign of Experiments (DoE)AnalytesInjection cyclesPolylactidesMAQUINAS Y MOTORES TERMICOSMatrix-assisted laser desorption/ionization-time-of-flight mass spectrometryGlass transitionDesign of experimentsGlass lasersThermo mechanicalMALDI TOF MSChromatographyMatrixMass spectrometrySignal to noiseTermoplàsticsOrganic ChemistryDegradation mechanismThermo-oxidative ageingStatistical design of experimentsMatrix-assisted laser desorption/ionizationInvestigation methodsMatrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)Polylactide (PLA)AgeingOligomersDegradation (geology)DesorptionDeep inspectionExperimentsPoly(lactide)European Polymer Journal
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Improving Teachers' Professionalism on an Experimental Basis

2013

International audience; While education economists have paid considerable attention to the performance of the education sectors, they have placed little emphasis on the management of the pedagogical process. In the context of developing countries, there are clear signs of weak management and too many school personnel neglect tasks deemed essential for student learning. Using data from a large - scale experiment conducted recently in Madagascar, thearticle analyzes the variations in impact of a set of management interventions designed to improve the engagement at work of public primary school teachers. While school - level interventions raise the teachers' level of professionalism on average…

JEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policy[SHS.EDU]Humanities and Social Sciences/EducationJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field Experiments[SHS.EDU] Humanities and Social Sciences/EducationJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of Education[ SHS.EDU ] Humanities and Social Sciences/Education[SHS.ECO]Humanities and Social Sciences/Economics and Financeprimary educationJEL : C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field ExperimentsMadagascar[ SHS.ECO ] Humanities and Social Sciences/Economies and financesteacher[SHS.ECO] Humanities and Social Sciences/Economics and FinanceJEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of EducationmanagementJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policy
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In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

In situPO Propylene oxideIV IntravenousP338 Poloxamer 338lcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_compoundn Sample sizeSD Standard deviationIM Intramuscularchemistry.chemical_classificationC0 Analyte plasma concentration at time zeroDoE Design of experimentsUV UltravioletPharmacology. TherapyK2.EDTA Potassium ethylenediaminetetraacetic acidLC–MS/MS Liquid chromatography-tandem mass spectrometryH&E Hematoxylin and eosintmax Sampling time to reach the maximum observed analyte plasma concentrationIn situ forming gelsCMC Critical micellar concentrationCmax Maximum observed analyte plasma concentrationIntramuscular injectionDN Dose normalizedGPT Gel point temperaturePLGA Poly-(DL-lactic-co-glycolic acid)TFA Trifluoroacetic acidCAN AcetonitrileATP Adenosine 5′ triphosphateSalt (chemistry)Polyethylene glycolPoloxamerArticlelcsh:Pharmacy and materia medicaPharmacokineticsIn vivoUHPLC Ultra-high performance liquid chromatographyPharmacokineticsAUClast Area under the analyte concentration versus time curve from time zero to the time of the last measurable (non-below quantification level) concentrationEO Ethylene oxideNMP N-methyl-2-pyrrolidoneComputingMethodologies_COMPUTERGRAPHICSAUC∞ Area under the analyte concentration vs time curve from time zero to infinite timeP407 Poloxamer 407In vitro releasePoloxamerCMT Critical micellar temperatureGel erosionIn vitrot1/2 Apparent terminal elimination half-lifechemistryMDR-TB Multi-drug resistant tuberculosisAUC80h Area under the analyte concentration versus time curve from time zero to 80 htlast Sampling time until the last measurable (non-below quantification level) analyte plasma concentrationMRM Multiple reaction monitoringNuclear chemistrySustained releaseInternational Journal of Pharmaceutics: X
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Profit vs morality: how unfair is labor market discrimination? Results from a survey experiment

2019

Using an original survey-experimental protocol, we study the normative acceptability of the trade-off between immoral profit (discrimination) and costly morality (non-discrimination). We test the causal influence of three factors: i) the origin of discrimination, ii) the steepness of the morality/profit trade-off and iii) anti-discriminatory moral injunctions. Contrasting with past experimental and attitudinal studies, we find that a significant minority of respondents believe that labor market discrimination is acceptable when morality results in profit loss. We also find that the three tested factors have significant effects on normative opinions. Respondents are more likely to choose pro…

profit/morality trade-offJEL: J - Labor and Demographic Economics/J.J2 - Demand and Supply of Labor/J.J2.J23 - Labor Demandvignettesarbitrage morale/profitmoral suasionvignette survey experimentJEL: J - Labor and Demographic Economics/J.J7 - Labor DiscriminationJEL: J - Labor and Demographic Economics/J.J7 - Labor Discrimination/J.J7.J78 - Public Policy[SHS.ECO] Humanities and Social Sciences/Economics and Finance[SHS.ECO]Humanities and Social Sciences/Economics and FinanceJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experimentsdiscriminationinjonctions morales
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LES DISCRIMINATIONS A L'EMBAUCHE DANS LA SPHERE PUBLIQUE : EFFETS RESPECTIFS DE L'ADRESSE ET DE L'ORIGINE

2016

Cette étude évalue la discrimination dans l’accès à l’emploi dans trois professions présentes à la fois dans le secteur privé et dans la Fonction Publique. Deux dimensions sont examinées : l’effet de la réputation du lieu de résidence et l’effet de l’origine maghrébine. Elle est réalisée sur données expérimentales de testing réalisé dans trois professions en tension pour lesquelles la discrimination devrait a priori être très réduite : les responsables administratifs de catégorie A, les techniciens de maintenance de catégorie B et les aides soignantes de catégorie C. Pour chaque profession, nous avons construit 3 profils fictifs de candidats à l’emploi similaires en tout point à l’exception…

JEL : C - Mathematical and Quantitative Methods/C.C8 - Data Collection and Data Estimation Methodology • Computer Programs/C.C8.C81 - Methodology for Collecting Estimating and Organizing Microeconomic Data • Data AccessJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field Experimentstesting.JEL: J - Labor and Demographic Economics/J.J4 - Particular Labor Markets/J.J4.J45 - Public Sector Labor Marketsfonction publiqueJEL: J - Labor and Demographic Economics/J.J7 - Labor Discrimination/J.J7.J71 - Discrimination[SHS.ECO]Humanities and Social Sciences/Economics and FinanceJEL : J - Labor and Demographic Economics/J.J4 - Particular Labor Markets/J.J4.J45 - Public Sector Labor Marketsoriginelieu de résidenceJEL : C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field ExperimentsJEL : J - Labor and Demographic Economics/J.J1 - Demographic Economics/J.J1.J15 - Economics of Minorities Races Indigenous Peoples and Immigrants • Non-labor DiscriminationJEL: C - Mathematical and Quantitative Methods/C.C8 - Data Collection and Data Estimation Methodology • Computer Programs/C.C8.C81 - Methodology for Collecting Estimating and Organizing Microeconomic Data • Data Access[ SHS.ECO ] Humanities and Social Sciences/Economies and financesdiscrimination à l’embaucheJEL: J - Labor and Demographic Economics/J.J1 - Demographic Economics/J.J1.J15 - Economics of Minorities Races Indigenous Peoples and Immigrants • Non-labor DiscriminationJEL : J - Labor and Demographic Economics/J.J7 - Labor Discrimination/J.J7.J71 - Discrimination[SHS.ECO] Humanities and Social Sciences/Economics and Finance
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Actuar para mejorar la implicacion en el trabajo de los docentes: resultados diferenciados de un experimento randomizado

2013

En ligne sur http://2013.economicsofeducation.com/user/pdfsesiones/106.pdf?PHPSESSID=vg6pgcqhd5dl52aenlhacj17k6; International audience; Utilizando datos de un experimento randomizado realizado en Madagascar durante dos años escolares completos, se evalúan las heterogeneidades de impacto de unas intervenciones específicamente diseñadas para mejorar la gestión del proceso pedagógico en la escuelas primarias. Nuestros resultados muestran que intervenciones intensivas y directas a lo largo de la jerarquía educativa permiten cambiar el comportamiento de los docentes de manera significativa. Sin embargo, el impacto medio del programa oculta una gran heterogeneidad. Los maestros que tenían pocos …

JEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policygestión[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationJEL: C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field ExperimentsdocentesJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of Education[ SHS.EDU ] Humanities and Social Sciences/Education[SHS.ECO]Humanities and Social Sciences/Economics and Financeeducación primariaJEL : C - Mathematical and Quantitative Methods/C.C9 - Design of Experiments/C.C9.C93 - Field ExperimentsMadagascar[ SHS.ECO ] Humanities and Social Sciences/Economies and finances[SHS.ECO] Humanities and Social Sciences/Economics and FinanceJEL : I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I21 - Analysis of EducationJEL: I - Health Education and Welfare/I.I2 - Education and Research Institutions/I.I2.I28 - Government Policy
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